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pilN pilN pilQ pilQ pilP pilP pilO pilO pilM pilM pilF pilF pilE pilE pilU pilU pilY1 pilY1 pilG pilG pilT pilT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pilNType 4 fimbrial biogenesis protein PilN; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (198 aa)    
Predicted Functional Partners:
pilQ
Type 4 fimbrial biogenesis outer membrane protein PilQ precursor; Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a 'porthole' allowing passage of the fimbrae through the outer membrane; Belongs to the bacterial secretin family. PilQ subfamily.
 
 
 0.999
pilP
Type 4 fimbrial biogenesis protein PilP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 
 0.999
pilO
Type 4 fimbrial biogenesis protein PilO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 
 0.999
pilM
Type 4 fimbrial biogenesis protein PilM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 
 0.999
pilF
Type 4 fimbrial biogenesis protein PilF; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.981
pilE
Type 4 fimbrial biogenesis protein PilE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
  
 0.980
pilU
Twitching motility protein PilU; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.959
pilY1
Type 4 fimbrial biogenesis protein PilY1; Involved in pilus assembly, twitching motility and adhesion to host cells. Primes type IV pili (T4P) assembly and is required for inclusion of minor pilins PilV, PilW and PilX to the surface pili. Stabilizes assembled pilus fibers likely by antagonizing retraction mediated by PilT. Calcium-binding and calcium release by PilY1 seem to be essential for twitching motility and for regulation of pilus retraction dynamics of PilT (By similarity).
 
  
 0.958
pilG
Twitching motility protein PilG; Is involved in pilus biosynthesis and twitching motility. May act as a single-domain response regulator whose function may be to receive a certain environmental signal(s) and then transduce that signal to the pilus assembly machinery via specific protein-protein interactions.
  
  
 0.957
pilT
Twitching motility protein PilT; May be involved in pilus retraction; Belongs to the GSP E family.
 
  
 0.955
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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