hutU protein (Pseudomonas aeruginosa) - STRING interaction network

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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Score

hutU

Urocanase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (559 aa)

Predicted Functional Partners:

hutI

0.999

PA5093

0.999

hutH

0.999

PA5106

0.980

hutC

0.979

PA5099

0.942

hutG

0.934

hutG-2

0.859

PA5096

0.848

PA5094

0.839

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PA5093	PA5094	PA5093	PA5094	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.951
PA5093	PA5096	PA5093	PA5096	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable binding protein component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.959
PA5093	PA5099	PA5093	PA5099	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the purine-cytosine permease (2.A.39) family.	0.909
PA5093	PA5106	PA5093	PA5106	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.846
PA5093	hutC	PA5093	PA5105	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Histidine utilization repressor HutC; Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer (By similarity).	0.880
PA5093	hutG	PA5093	PA5091	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	N-formylglutamate amidohydrolase; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.972
PA5093	hutG-2	PA5093	PA3175	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable arginase family protein; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.	0.683
PA5093	hutH	PA5093	PA5098	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Histidine ammonia-lyase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the PAL/histidase family.	0.991
PA5093	hutI	PA5093	PA5092	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Imidazolone-5-propionate hydrolase HutI; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the metallo-dependent hydrolases superfamily. HutI family.	0.999
PA5093	hutU	PA5093	PA5100	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Urocanase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.999
PA5094	PA5093	PA5094	PA5093	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.951
PA5094	PA5096	PA5094	PA5096	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable binding protein component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.998
PA5094	PA5099	PA5094	PA5099	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the purine-cytosine permease (2.A.39) family.	0.974
PA5094	PA5106	PA5094	PA5106	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.538
PA5094	hutG	PA5094	PA5091	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	N-formylglutamate amidohydrolase; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.970
PA5094	hutH	PA5094	PA5098	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Histidine ammonia-lyase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the PAL/histidase family.	0.918
PA5094	hutI	PA5094	PA5092	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Imidazolone-5-propionate hydrolase HutI; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the metallo-dependent hydrolases superfamily. HutI family.	0.951
PA5094	hutU	PA5094	PA5100	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Urocanase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.839
PA5096	PA5093	PA5096	PA5093	Probable binding protein component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.959
PA5096	PA5094	PA5096	PA5094	Probable binding protein component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).	0.998