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PA5106 PA5106 hutG hutG hutI hutI hutG-2 hutG-2 hutU hutU hutH hutH hutC hutC PA5104 PA5104 codA codA PA5093 PA5093 PA0148 PA0148
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA5106Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (453 aa)    
Predicted Functional Partners:
hutG
N-formylglutamate amidohydrolase; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 
 0.998
hutI
Imidazolone-5-propionate hydrolase HutI; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
 0.995
hutG-2
Probable arginase family protein; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
  
 
 0.981
hutU
Urocanase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.980
hutH
Histidine ammonia-lyase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the PAL/histidase family.
 
  
 0.968
hutC
Histidine utilization repressor HutC; Repressor which binds to the hutP region in the histidine utilization (hut) operon. It blocks the expression of all the hut genes in the absence of inducer (By similarity).
 
  
 0.961
PA5104
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
    0.947
codA
Cytosine deaminase; Product name confidence: Class 2 (High similarity to functionally studied protein).
     
 0.890
PA5093
Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.846
PA0148
Probable adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
   
 
 0.838
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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