node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA1435 | PA5158 | PA1435 | PA5158 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.650 |
PA2019 | PA5158 | PA2019 | PA5158 | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein precursor; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.709 |
PA2019 | mexA | PA2019 | PA0425 | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein precursor; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor; The periplasmic linker component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Required for assembly of the MexA/MexB/OprM complex. Implicated in the secretion of the siderophore pyoverdine; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.918 |
PA3310 | PA5157 | PA3310 | PA5157 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.883 |
PA3310 | PA5158 | PA3310 | PA5158 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.883 |
PA3523 | PA5158 | PA3523 | PA5158 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.673 |
PA5157 | PA3310 | PA5157 | PA3310 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.883 |
PA5157 | PA5158 | PA5157 | PA5158 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.987 |
PA5157 | PA5159 | PA5157 | PA5159 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Multidrug resistance protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.890 |
PA5157 | PA5160 | PA5157 | PA5160 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Drug efflux transporter; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the major facilitator superfamily. | 0.886 |
PA5158 | PA1435 | PA5158 | PA1435 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.650 |
PA5158 | PA2019 | PA5158 | PA2019 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein precursor; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.709 |
PA5158 | PA3310 | PA5158 | PA3310 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.883 |
PA5158 | PA3523 | PA5158 | PA3523 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.673 |
PA5158 | PA5157 | PA5158 | PA5157 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.987 |
PA5158 | PA5159 | PA5158 | PA5159 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Multidrug resistance protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.989 |
PA5158 | PA5160 | PA5158 | PA5160 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Drug efflux transporter; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the major facilitator superfamily. | 0.863 |
PA5158 | mexA | PA5158 | PA0425 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor; The periplasmic linker component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Required for assembly of the MexA/MexB/OprM complex. Implicated in the secretion of the siderophore pyoverdine; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.696 |
PA5158 | mexC | PA5158 | PA4599 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexC precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.720 |
PA5158 | mexE | PA5158 | PA2493 | Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexE precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.697 |