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PA5158 PA5158 PA5159 PA5159 PA5157 PA5157 PA3310 PA3310 PA5160 PA5160 mexC mexC PA2019 PA2019 mexE mexE mexA mexA PA3523 PA3523 PA1435 PA1435
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA5158Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (492 aa)    
Predicted Functional Partners:
PA5159
Multidrug resistance protein; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 
 0.989
PA5157
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.987
PA3310
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.883
PA5160
Drug efflux transporter; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the major facilitator superfamily.
 
  
 0.863
mexC
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexC precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.720
PA2019
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein precursor; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.709
mexE
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexE precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.697
mexA
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor; The periplasmic linker component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Required for assembly of the MexA/MexB/OprM complex. Implicated in the secretion of the siderophore pyoverdine; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.696
PA3523
Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.673
PA1435
Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.650
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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