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fdhD fdhD PA5181 PA5181 PA2714 PA2714 fdhE fdhE moaC moaC moaA1 moaA1 selB selB selA selA selD selD fdnG fdnG rhdA rhdA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fdhDConserved hypothetical protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (279 aa)    
Predicted Functional Partners:
PA5181
Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.997
PA2714
Probable molybdopterin oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.927
fdhE
FdhE protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
  
 0.845
moaC
Molybdopterin biosynthetic protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
  
 0.843
moaA1
Molybdopterin biosynthetic protein A1; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.830
selB
Selenocysteine-specific elongation factor; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.810
selA
L-seryl-tRNA(ser) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.765
selD
Selenophosphate synthetase; Synthesizes selenophosphate from selenide and ATP.
 
   
 0.754
fdnG
Formate dehydrogenase-O, major subunit; Product name confidence: Class 2: Function of highly similar gene experimentally demonstrated in another organism (and gene context consistent in terms of pathways its involved in, if known).
 
 
 0.742
rhdA
Thiosulfate:cyanide sulfurtransferase; Catalyzes the sulfur transfer reaction from thiosulfate to cyanide, thus converting cyanide to the less toxic thiocyanate. Contributes to P.aeruginosa survival under cyanogenic conditions, and thus provides the bacterium with a defense mechanism against endogenous cyanide toxicity. Is the main cytoplasmic rhodanese in P.aeruginosa, accounting for 90% of total rhodanese activity.
      
 0.717
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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