node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hfq | pnp | PA4944 | PA4740 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.961 |
hfq | rho | PA4944 | PA5239 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.926 |
hfq | rne | PA4944 | PA2976 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.954 |
hfq | rpoA | PA4944 | PA4238 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.741 |
hfq | rpoC | PA4944 | PA4269 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA-directed RNA polymerase beta* chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.435 |
hfq | rsmA | PA4944 | PA0905 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | RsmA, regulator of secondary metabolites; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). Probably [...] | 0.976 |
nusA | nusG | PA4745 | PA4275 | N utilization substance protein A; Participates in both transcription termination and antitermination. | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | 0.990 |
nusA | pnp | PA4745 | PA4740 | N utilization substance protein A; Participates in both transcription termination and antitermination. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.964 |
nusA | rho | PA4745 | PA5239 | N utilization substance protein A; Participates in both transcription termination and antitermination. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.933 |
nusA | rpoA | PA4745 | PA4238 | N utilization substance protein A; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.992 |
nusA | rpoB | PA4745 | PA4270 | N utilization substance protein A; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.996 |
nusA | rpoC | PA4745 | PA4269 | N utilization substance protein A; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase beta* chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.980 |
nusA | yidC | PA4745 | PA5568 | N utilization substance protein A; Participates in both transcription termination and antitermination. | Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.422 |
nusG | nusA | PA4275 | PA4745 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | N utilization substance protein A; Participates in both transcription termination and antitermination. | 0.990 |
nusG | pnp | PA4275 | PA4740 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.804 |
nusG | rho | PA4275 | PA5239 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.980 |
nusG | rpoA | PA4275 | PA4238 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.991 |
nusG | rpoB | PA4275 | PA4270 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.996 |
nusG | rpoC | PA4275 | PA4269 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | DNA-directed RNA polymerase beta* chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.986 |
nusG | yidC | PA4275 | PA5568 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.514 |