node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA0670 | dinB | PA0670 | PA0923 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | DNA Polymerase IV, DinB; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.688 |
PA0670 | fkl | PA0670 | PA5254 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | 0.430 |
PA1068 | dnaK | PA1068 | PA4761 | Probable heat shock protein (hsp90 family); Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.913 |
PA1068 | fkl | PA1068 | PA5254 | Probable heat shock protein (hsp90 family); Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | 0.645 |
algP | fkl | PA5253 | PA5254 | Alginate regulatory protein AlgP; The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e. under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process. | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | 0.604 |
apaH | dnaK | PA0590 | PA4761 | Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.499 |
apaH | fkl | PA0590 | PA5254 | Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | 0.679 |
cobL | fkl | PA2907 | PA5254 | Precorrin-6y-dependent methyltransferase CobL; Catalyzes the methylation of both C-5 and C-15 in precorrin- 6Y to form precorrin-8X. | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | 0.883 |
dinB | PA0670 | PA0923 | PA0670 | DNA Polymerase IV, DinB; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.688 |
dinB | fkl | PA0923 | PA5254 | DNA Polymerase IV, DinB; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | 0.430 |
dinB | rpoB | PA0923 | PA4270 | DNA Polymerase IV, DinB; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.525 |
dnaK | PA1068 | PA4761 | PA1068 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Probable heat shock protein (hsp90 family); Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.913 |
dnaK | apaH | PA4761 | PA0590 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.499 |
dnaK | fkl | PA4761 | PA5254 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | 0.460 |
dnaK | htpG | PA4761 | PA1596 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity. | 0.998 |
dnaK | infA | PA4761 | PA2619 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Initiation factor; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 0.488 |
dnaK | rpoB | PA4761 | PA4270 | DnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.901 |
fkl | PA0670 | PA5254 | PA0670 | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.430 |
fkl | PA1068 | PA5254 | PA1068 | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | Probable heat shock protein (hsp90 family); Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.645 |
fkl | algP | PA5254 | PA5253 | Probable peptidyl-prolyl cis-trans isomerase, FkbP-type; PPIases accelerate the folding of proteins; Belongs to the FKBP-type PPIase family. | Alginate regulatory protein AlgP; The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e. under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process. | 0.604 |