node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA2577 | lrp | PA2577 | PA5308 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.811 |
PA5306 | PA5307 | PA5306 | PA5307 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.946 |
PA5306 | lrp | PA5306 | PA5308 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.514 |
PA5307 | PA5306 | PA5307 | PA5306 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.946 |
PA5307 | lrp | PA5307 | PA5308 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.534 |
PA5309 | lrp | PA5309 | PA5308 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.503 |
dadA | dadX | PA5304 | PA5302 | D-amino acid dehydrogenase, small subunit; Catalyzes the oxidative deamination of D-amino acids. Has very broad substrate specificity; all the D-amino acids tested can be used as the substrate except D-Glu and D-Gln. Participates in the utilization of several D-amino acids as the sole source of nitrogen, i.e. D-alanine, D-histidine, D-phenylalanine, D-serine, D-threonine, and D-valine. | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | 0.993 |
dadA | lrp | PA5304 | PA5308 | D-amino acid dehydrogenase, small subunit; Catalyzes the oxidative deamination of D-amino acids. Has very broad substrate specificity; all the D-amino acids tested can be used as the substrate except D-Glu and D-Gln. Participates in the utilization of several D-amino acids as the sole source of nitrogen, i.e. D-alanine, D-histidine, D-phenylalanine, D-serine, D-threonine, and D-valine. | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.508 |
dadX | dadA | PA5302 | PA5304 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | D-amino acid dehydrogenase, small subunit; Catalyzes the oxidative deamination of D-amino acids. Has very broad substrate specificity; all the D-amino acids tested can be used as the substrate except D-Glu and D-Gln. Participates in the utilization of several D-amino acids as the sole source of nitrogen, i.e. D-alanine, D-histidine, D-phenylalanine, D-serine, D-threonine, and D-valine. | 0.993 |
dadX | lrp | PA5302 | PA5308 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.590 |
dadX | putA | PA5302 | PA0782 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Proline dehydrogenase PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.481 |
fis | hfq | PA4853 | PA4944 | DNA-binding protein Fis; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the transcriptional regulatory Fis family. | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.870 |
fis | lrp | PA4853 | PA5308 | DNA-binding protein Fis; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the transcriptional regulatory Fis family. | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.717 |
fis | rpoS | PA4853 | PA3622 | DNA-binding protein Fis; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the transcriptional regulatory Fis family. | Sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.813 |
hfq | fis | PA4944 | PA4853 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA-binding protein Fis; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the transcriptional regulatory Fis family. | 0.870 |
hfq | lrp | PA4944 | PA5308 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.552 |
hfq | rpoS | PA4944 | PA3622 | Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.963 |
lrp | PA2577 | PA5308 | PA2577 | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.811 |
lrp | PA5306 | PA5308 | PA5306 | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.514 |
lrp | PA5307 | PA5308 | PA5307 | Leucine-responsive regulatory protein; Product name confidence: Class 2 (High similarity to functionally studied protein). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.534 |