STRINGSTRING
PA5364 PA5364 PA1243 PA1243 ercS-2 ercS-2 fleS fleS gacS gacS PA0930 PA0930 PA1158 PA1158 pfeS pfeS PA2524 PA2524 PA2177 PA2177 PA0599 PA0599
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA5364Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (300 aa)    
Predicted Functional Partners:
PA1243
Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.881
ercS-2
ErcS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.859
fleS
Two-component sensor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.806
gacS
Sensor/response regulator hybrid; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 
 0.805
PA0930
Two-component sensor; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 
 0.777
PA1158
Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.774
pfeS
Two-component sensor PfeS; Member of the two-component regulatory system PfeR/PfeS. May activate PfeR by phosphorylation.
 
 
 0.769
PA2524
Probable two-component sensor; Member of a two-component regulatory system.
 
 
 0.768
PA2177
Probable sensor/response regulator hybrid; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.753
PA0599
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
    0.751
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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