STRINGSTRING
soxB soxB soxD soxD soxA soxA soxG soxG glyA1 glyA1 dgcA dgcA PA5397 PA5397 gbcA gbcA PA5396 PA5396 ltaA ltaA gbcB gbcB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
soxBSarcosine oxidase beta subunit; Class 1: Function experimentally demonstrated in P. aeruginosa. (416 aa)    
Predicted Functional Partners:
soxD
Sarcosine oxidase delta subunit; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 0.999
soxA
Sarcosine oxidase alpha subunit; Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the GcvT family.
 
 0.999
soxG
Sarcosine oxidase gamma subunit; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 0.999
glyA1
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.974
dgcA
DgcA, Dimethylglycine catabolism; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.959
PA5397
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
    0.947
gbcA
GbcA; Class 1: Function experimentally demonstrated in P. aeruginosa.
  
    0.947
PA5396
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
    0.942
ltaA
Low specificity l-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
  
 
 0.932
gbcB
GbcB; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.928
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.