STRINGSTRING
poxA poxA hisZ hisZ mifS mifS mifR mifR efp efp PA5514 PA5514 poxB poxB hisS hisS PA4137 PA4137 PA5307 PA5307 PA0926 PA0926
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
poxAHypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (292 aa)    
Predicted Functional Partners:
hisZ
Conserved hypothetical protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity).
      
 0.809
mifS
MifS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.781
mifR
MifR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
     
 0.762
efp
Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
   
  
 0.723
PA5514
Probable beta-lactamase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
     
 0.713
poxB
Pyruvate dehydrogenase (cytochrome); Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the TPP enzyme family.
      
 0.701
hisS
histidyl-tRNA synthetase; Product name confidence: Class 2 (High similarity to functionally studied protein).
      
 0.691
PA4137
Probable porin; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
     0.611
PA5307
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
    0.597
PA0926
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.587
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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