STRINGSTRING
PFL_0016 PFL_0016 waaA waaA htrB htrB kdsD kdsD lpxD lpxD lpxB lpxB lpxK lpxK tag_2 tag_2 lpxA lpxA PFL_0017 PFL_0017 lpxC lpxC
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query proteins and first shell of interactors
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second shell of interactors
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experimentally determined
Predicted Interactions
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textmining
co-expression
protein homology
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PFL_0016Putative lipid A biosynthesis lauroyl acyltransferase; Identified by similarity to SP:P24187; match to protein family HMM PF03279. (295 aa)    
Predicted Functional Partners:
waaA
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
  
 0.969
htrB
Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
  
  
0.921
kdsD
Arabinose 5-phosphate isomerase; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393.
 
   
 0.786
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.785
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.780
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
  
 0.742
tag_2
DNA-3-methyladenine glycosylase I; Identified by similarity to SP:P05100; match to protein family HMM PF03352; match to protein family HMM TIGR00624.
  
  
 0.724
lpxA
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.686
PFL_0017
Conserved hypothetical protein; Identified by match to protein family HMM PF07238.
  
  
 0.679
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.672
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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