node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_0112 | PFL_3068 | PFL_0112 | PFL_3068 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | 0.929 |
PFL_0112 | acoC | PFL_0112 | PFL_2172 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | 0.921 |
PFL_0112 | acsA_1 | PFL_0112 | PFL_4522 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.929 |
PFL_0112 | acsA_2 | PFL_0112 | PFL_5281 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.929 |
PFL_0112 | glcB | PFL_0112 | PFL_5700 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.921 |
PFL_0112 | pta | PFL_0112 | PFL_0938 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.943 |
PFL_0112 | sdhA | PFL_0112 | PFL_1716 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P10444; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.915 |
PFL_0112 | sdhB | PFL_0112 | PFL_1717 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P07014; match to protein family HMM TIGR00384. | 0.922 |
PFL_0112 | sucC | PFL_0112 | PFL_1721 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.936 |
PFL_0112 | sucD | PFL_0112 | PFL_1722 | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.930 |
PFL_3068 | PFL_0112 | PFL_3068 | PFL_0112 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | 0.929 |
PFL_3068 | acoC | PFL_3068 | PFL_2172 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | 0.919 |
PFL_3068 | acsA_1 | PFL_3068 | PFL_4522 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.923 |
PFL_3068 | acsA_2 | PFL_3068 | PFL_5281 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.922 |
PFL_3068 | glcB | PFL_3068 | PFL_5700 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.950 |
PFL_3068 | pta | PFL_3068 | PFL_0938 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.945 |
PFL_3068 | sucC | PFL_3068 | PFL_1721 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.865 |
PFL_3068 | sucD | PFL_3068 | PFL_1722 | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.854 |
acoC | PFL_0112 | PFL_2172 | PFL_0112 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | Succinate CoA transferase; Identified by similarity to SP:P38946; match to protein family HMM PF02550; match to protein family HMM TIGR03458. | 0.921 |
acoC | PFL_3068 | PFL_2172 | PFL_3068 | Acetoin dehydrogenase E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to SP:Q59695; match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF00975. | AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | 0.919 |