node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_2465 | cobB-3 | PFL_2465 | PFL_2453 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | 0.918 |
PFL_2465 | mazG | PFL_2465 | PFL_4445 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | Nucleoside triphosphate pyrophosphohydrolase; Identified by similarity to SP:P0AEY3; match to protein family HMM PF01503; match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.904 |
PFL_2465 | nadD | PFL_2465 | PFL_5455 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.911 |
PFL_2465 | nadE_1 | PFL_2465 | PFL_2468 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.958 |
PFL_2465 | nadE_2 | PFL_2465 | PFL_0593 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.921 |
PFL_2465 | nadK | PFL_2465 | PFL_3286 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.927 |
PFL_2465 | pntAA | PFL_2465 | PFL_0115 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | NAD(P) transhydrogenase, alpha subunit part 1; Identified by similarity to SP:Q60164; match to protein family HMM PF01262; match to protein family HMM PF05222. | 0.905 |
PFL_2465 | pntAB | PFL_2465 | PFL_0114 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | NAD(P) transhydrogenase, alpha subunit part 2; Identified by similarity to SP:Q59764. | 0.905 |
PFL_2465 | pntB | PFL_2465 | PFL_0113 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.904 |
PFL_2465 | sthA | PFL_2465 | PFL_1958 | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.901 |
cobB-3 | PFL_2465 | PFL_2453 | PFL_2465 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125. | 0.918 |
cobB-3 | mazG | PFL_2453 | PFL_4445 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | Nucleoside triphosphate pyrophosphohydrolase; Identified by similarity to SP:P0AEY3; match to protein family HMM PF01503; match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.901 |
cobB-3 | nadD | PFL_2453 | PFL_5455 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.921 |
cobB-3 | nadE_1 | PFL_2453 | PFL_2468 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.915 |
cobB-3 | nadE_2 | PFL_2453 | PFL_0593 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.915 |
cobB-3 | nadK | PFL_2453 | PFL_3286 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.919 |
cobB-3 | pntAA | PFL_2453 | PFL_0115 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | NAD(P) transhydrogenase, alpha subunit part 1; Identified by similarity to SP:Q60164; match to protein family HMM PF01262; match to protein family HMM PF05222. | 0.909 |
cobB-3 | pntAB | PFL_2453 | PFL_0114 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | NAD(P) transhydrogenase, alpha subunit part 2; Identified by similarity to SP:Q59764. | 0.905 |
cobB-3 | pntB | PFL_2453 | PFL_0113 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.901 |
cobB-3 | sthA | PFL_2453 | PFL_1958 | NAD-dependent deacetylase; Identified by similarity to SP:Q9I4L0; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.911 |