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PFL_0222 PFL_0222 PFL_0221 PFL_0221 birA birA PFL_0223 PFL_0223 hisE hisE PFL_0224 PFL_0224 xdhB xdhB xdhA xdhA guaA guaA yeaZ yeaZ ppnP ppnP
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
PFL_0222Putative guanine deaminase; Identified by similarity to SP:O34598; match to protein family HMM PF00383. (153 aa)    
Predicted Functional Partners:
PFL_0221
Transporter, major facilitator family; Identified by match to protein family HMM PF07690.
       0.791
birA
Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.782
PFL_0223
Ankyrin repeat protein; Identified by match to protein family HMM PF00023.
   
 
 0.728
hisE
phosphoribosyl-ATP diphosphatase; Identified by match to protein family HMM PF01503; match to protein family HMM TIGR03188.
   
  
 0.560
PFL_0224
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
 
     0.558
xdhB
Xanthine dehydrogenase, molybdopterin binding subunit; Identified by similarity to GB:CAA04470.2; match to protein family HMM PF01315; match to protein family HMM PF02738; match to protein family HMM TIGR02965.
    
 0.539
xdhA
Xanthine dehydrogenase, small subunit; Identified by similarity to GB:CAA04469.1; match to protein family HMM PF00111; match to protein family HMM PF00941; match to protein family HMM PF01799; match to protein family HMM PF03450; match to protein family HMM TIGR02963.
    
  0.532
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.527
yeaZ
Peptidase, M22 family; Identified by similarity to SP:P76256; match to protein family HMM PF00814.
 
  
 0.511
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.499
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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