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msrA_2 msrA_2 msrB msrB polA polA PFL_4183 PFL_4183 dsbD dsbD PFL_0507 PFL_0507 dsbE dsbE PFL_4272 PFL_4272 PFL_4455 PFL_4455 PFL_5918 PFL_5918 metH metH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
msrA_2Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (215 aa)    
Predicted Functional Partners:
msrB
methionine-R-sulfoxide reductase; Identified by similarity to SP:P39903; match to protein family HMM PF01641; match to protein family HMM TIGR00357; Belongs to the MsrB Met sulfoxide reductase family.
 
 0.991
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.846
PFL_4183
Antioxidant, AhpC family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.
   
 0.741
dsbD
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
   
 
 0.673
PFL_0507
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254.
       0.655
dsbE
Thiol:disulfide interchange protein DsbE; Identified by similarity to SP:P0AA86; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385.
   
 0.624
PFL_4272
Putative lipoprotein.
   
 0.624
PFL_4455
Antioxidant, AhpC/TSA family; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534.
   
 0.624
PFL_5918
Conserved hypothetical protein.
   
 0.622
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
  
 0.596
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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