node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_2451 | add | PFL_2451 | PFL_0719 | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.900 |
PFL_2451 | amn | PFL_2451 | PFL_5424 | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.913 |
PFL_2451 | apt | PFL_2451 | PFL_1909 | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.905 |
PFL_2451 | ppnP | PFL_2451 | PFL_4201 | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
PFL_2451 | rihA | PFL_2451 | PFL_2107 | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by similarity to SP:P41409; match to protein family HMM PF01156; Belongs to the IUNH family. | 0.901 |
PFL_2451 | surE | PFL_2451 | PFL_1204 | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.905 |
PFL_5138 | add | PFL_5138 | PFL_0719 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.936 |
PFL_5138 | apt | PFL_5138 | PFL_1909 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.931 |
PFL_5138 | guaA | PFL_5138 | PFL_4939 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.954 |
PFL_5138 | ppnP | PFL_5138 | PFL_4201 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.900 |
PFL_5138 | rihA | PFL_5138 | PFL_2107 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by similarity to SP:P41409; match to protein family HMM PF01156; Belongs to the IUNH family. | 0.920 |
PFL_5138 | surE | PFL_5138 | PFL_1204 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.914 |
PFL_5138 | xdhA | PFL_5138 | PFL_1889 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Xanthine dehydrogenase, small subunit; Identified by similarity to GB:CAA04469.1; match to protein family HMM PF00111; match to protein family HMM PF00941; match to protein family HMM PF01799; match to protein family HMM PF03450; match to protein family HMM TIGR02963. | 0.900 |
PFL_5138 | xdhB | PFL_5138 | PFL_1888 | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | Xanthine dehydrogenase, molybdopterin binding subunit; Identified by similarity to GB:CAA04470.2; match to protein family HMM PF01315; match to protein family HMM PF02738; match to protein family HMM TIGR02965. | 0.901 |
add | PFL_2451 | PFL_0719 | PFL_2451 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | 0.900 |
add | PFL_5138 | PFL_0719 | PFL_5138 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 0.936 |
add | amn | PFL_0719 | PFL_5424 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.934 |
add | apt | PFL_0719 | PFL_1909 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.945 |
add | guaA | PFL_0719 | PFL_4939 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.643 |
add | ppnP | PFL_0719 | PFL_4201 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.904 |