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PFL_0729 PFL_0729 PFL_0730 PFL_0730 tmk tmk yicE yicE PFL_1380 PFL_1380 dut dut PFL_3631 PFL_3631 mazG mazG gcvT_1 gcvT_1 folA folA PFL_2370 PFL_2370
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PFL_0729Conserved hypothetical protein; Identified by match to protein family HMM PF01205; match to protein family HMM PF09186. (193 aa)    
Predicted Functional Partners:
PFL_0730
Transcriptional regulator, TetR family; Identified by similarity to SP:P0ACU2; match to protein family HMM PF00440; match to protein family HMM PF08362.
       0.802
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
  0.563
yicE
High-affinity xanthine transporter, NCS2 family, YicE; See PMID: 16096267 for more information; identified by similarity to SP:P0AGM9; match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173.
       0.562
PFL_1380
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF02826.
    
  0.520
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
  0.515
PFL_3631
Riboflavin biosynthesis protein RibD C-terminal domain protein; Identified by match to protein family HMM PF01872.
     
  0.499
mazG
Nucleoside triphosphate pyrophosphohydrolase; Identified by similarity to SP:P0AEY3; match to protein family HMM PF01503; match to protein family HMM PF03819; match to protein family HMM TIGR00444.
     
  0.499
gcvT_1
Aminomethyltransferase; Identified by match to protein family HMM PF01571; match to protein family HMM PF08669; match to protein family HMM TIGR00528.
     
  0.499
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
  0.499
PFL_2370
Conserved hypothetical protein; Identified by match to protein family HMM PF04816.
   
    0.459
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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