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mmsA_2 mmsA_2 mmsB mmsB prpC prpC PFL_3068 PFL_3068 acsA_1 acsA_1 acsA_2 acsA_2 PFL_0733 PFL_0733 PFL_1303 PFL_1303 PFL_2928 PFL_2928 xylC xylC PFL_3648 PFL_3648
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
mmsA_2Methylmalonate-semialdehyde dehydrogenase (acylating); Identified by similarity to SP:P28810; match to protein family HMM PF00171; match to protein family HMM TIGR01722. (508 aa)    
Predicted Functional Partners:
mmsB
3-hydroxyisobutyrate dehydrogenase; Identified by similarity to SP:P28811; match to protein family HMM PF03446; match to protein family HMM TIGR01692; Belongs to the HIBADH-related family.
 
 
 0.989
prpC
2-methylcitrate synthase; Identified by similarity to SP:P31660; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.
  
 0.935
PFL_3068
AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501.
  
 0.932
acsA_1
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.932
acsA_2
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.932
PFL_0733
Beta-alanine--pyruvate transaminase; Identified by similarity to SP:P28269; match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.928
PFL_1303
Identified by similarity to SP:P23523; match to protein family HMM PF03446.
 
 
 0.927
PFL_2928
NAD binding domain protein; Identified by match to protein family HMM PF03446.
 
 
 0.927
xylC
Benzaldehyde dehydrogenase; Identified by similarity to SP:P43503; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.924
PFL_3648
Identified by similarity to GB:AAK18072.1; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.921
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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