node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_1166 | PFL_1167 | PFL_1166 | PFL_1167 | Identified by match to protein family HMM PF00332; match to protein family HMM PF00535. | Identified by match to protein family HMM PF00899. | 0.591 |
PFL_1166 | dapE | PFL_1166 | PFL_1165 | Identified by match to protein family HMM PF00332; match to protein family HMM PF00535. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.531 |
PFL_1167 | PFL_1166 | PFL_1167 | PFL_1166 | Identified by match to protein family HMM PF00899. | Identified by match to protein family HMM PF00332; match to protein family HMM PF00535. | 0.591 |
PFL_1167 | PFL_4434 | PFL_1167 | PFL_4434 | Identified by match to protein family HMM PF00899. | O-methyltransferase; Identified by match to protein family HMM PF01596. | 0.435 |
PFL_1167 | PFL_5157 | PFL_1167 | PFL_5157 | Identified by match to protein family HMM PF00899. | ThiF/MoeB domain protein; Identified by similarity to SP:P12282; similarity to SP:P30138; match to protein family HMM PF00899; match to protein family HMM PF05237. | 0.453 |
PFL_1167 | dapE | PFL_1167 | PFL_1165 | Identified by match to protein family HMM PF00899. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.414 |
PFL_1167 | thiG | PFL_1167 | PFL_5850 | Identified by match to protein family HMM PF00899. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.500 |
PFL_4434 | PFL_1167 | PFL_4434 | PFL_1167 | O-methyltransferase; Identified by match to protein family HMM PF01596. | Identified by match to protein family HMM PF00899. | 0.435 |
PFL_5157 | PFL_1167 | PFL_5157 | PFL_1167 | ThiF/MoeB domain protein; Identified by similarity to SP:P12282; similarity to SP:P30138; match to protein family HMM PF00899; match to protein family HMM PF05237. | Identified by match to protein family HMM PF00899. | 0.453 |
PFL_5157 | thiG | PFL_5157 | PFL_5850 | ThiF/MoeB domain protein; Identified by similarity to SP:P12282; similarity to SP:P30138; match to protein family HMM PF00899; match to protein family HMM PF05237. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.924 |
dapE | PFL_1166 | PFL_1165 | PFL_1166 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Identified by match to protein family HMM PF00332; match to protein family HMM PF00535. | 0.531 |
dapE | PFL_1167 | PFL_1165 | PFL_1167 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Identified by match to protein family HMM PF00899. | 0.414 |
thiG | PFL_1167 | PFL_5850 | PFL_1167 | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | Identified by match to protein family HMM PF00899. | 0.500 |
thiG | PFL_5157 | PFL_5850 | PFL_5157 | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | ThiF/MoeB domain protein; Identified by similarity to SP:P12282; similarity to SP:P30138; match to protein family HMM PF00899; match to protein family HMM PF05237. | 0.924 |