node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_1185 | cdsA_1 | PFL_1185 | PFL_1181 | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | 0.460 |
PFL_1185 | dxr | PFL_1185 | PFL_1182 | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.477 |
PFL_1185 | frr | PFL_1185 | PFL_1179 | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.612 |
PFL_1185 | lpxD | PFL_1185 | PFL_1186 | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.939 |
PFL_1185 | pyrH | PFL_1185 | PFL_1178 | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.575 |
PFL_1185 | rseP | PFL_1185 | PFL_1183 | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | RIP metalloprotease RseP; Identified by similarity to SP:P0AEH1; match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054. | 0.751 |
PFL_1185 | uppS | PFL_1185 | PFL_1180 | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.460 |
PFL_1185 | yaeT | PFL_1185 | PFL_1184 | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.944 |
cdsA_1 | PFL_1185 | PFL_1181 | PFL_1185 | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | 0.460 |
cdsA_1 | dxr | PFL_1181 | PFL_1182 | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.950 |
cdsA_1 | frr | PFL_1181 | PFL_1179 | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.903 |
cdsA_1 | lpxD | PFL_1181 | PFL_1186 | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.624 |
cdsA_1 | pyrH | PFL_1181 | PFL_1178 | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.953 |
cdsA_1 | rseP | PFL_1181 | PFL_1183 | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | RIP metalloprotease RseP; Identified by similarity to SP:P0AEH1; match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054. | 0.856 |
cdsA_1 | uppS | PFL_1181 | PFL_1180 | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.979 |
cdsA_1 | yaeT | PFL_1181 | PFL_1184 | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.618 |
dxr | PFL_1185 | PFL_1182 | PFL_1185 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Outer membrane protein, Skp family; Identified by similarity to SP:P31519; match to protein family HMM PF03938. | 0.477 |
dxr | cdsA_1 | PFL_1182 | PFL_1181 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Phosphatidate cytidylyltransferase; Identified by similarity to SP:P0ABG1; match to protein family HMM PF01148; Belongs to the CDS family. | 0.950 |
dxr | frr | PFL_1182 | PFL_1179 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.870 |
dxr | lpxD | PFL_1182 | PFL_1186 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.515 |