node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_1200 | fghA | PFL_1200 | PFL_1201 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.999 |
PFL_1200 | ispF | PFL_1200 | PFL_1202 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.502 |
PFL_1200 | pcm | PFL_1200 | PFL_1205 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | 0.501 |
PFL_1200 | surE | PFL_1200 | PFL_1204 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.491 |
PFL_1200 | truD | PFL_1200 | PFL_1203 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.506 |
fghA | PFL_1200 | PFL_1201 | PFL_1200 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | 0.999 |
fghA | ispF | PFL_1201 | PFL_1202 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.649 |
fghA | nlpD | PFL_1201 | PFL_1206 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | Putative lipoprotein NlpD; Identified by similarity to SP:P0ADA4; match to protein family HMM PF01476; match to protein family HMM PF01551. | 0.432 |
fghA | pcm | PFL_1201 | PFL_1205 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | 0.651 |
fghA | surE | PFL_1201 | PFL_1204 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.642 |
fghA | truD | PFL_1201 | PFL_1203 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.647 |
gltB | nuoD | PFL_0453 | PFL_3899 | Glutamate synthase, large subunit; Identified by similarity to SP:P09831; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | NADH-quinone oxidoreductase, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.582 |
gltB | pcm | PFL_0453 | PFL_1205 | Glutamate synthase, large subunit; Identified by similarity to SP:P09831; match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | 0.450 |
ispE | ispF | PFL_5163 | PFL_1202 | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.986 |
ispE | pcm | PFL_5163 | PFL_1205 | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | 0.596 |
ispF | PFL_1200 | PFL_1202 | PFL_1200 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818. | 0.502 |
ispF | fghA | PFL_1202 | PFL_1201 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.649 |
ispF | ispE | PFL_1202 | PFL_5163 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.986 |
ispF | nlpD | PFL_1202 | PFL_1206 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | Putative lipoprotein NlpD; Identified by similarity to SP:P0ADA4; match to protein family HMM PF01476; match to protein family HMM PF01551. | 0.557 |
ispF | pcm | PFL_1202 | PFL_1205 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | 0.802 |