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PFL_1860 PFL_1860 prpB prpB PFL_2433 PFL_2433 glcC glcC pdhR pdhR prpC prpC prpF prpF acnD acnD PFL_1857 PFL_1857 PFL_1858 PFL_1858 PFL_1859 PFL_1859
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PFL_1860Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729. (240 aa)    
Predicted Functional Partners:
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.854
PFL_2433
Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.
  
  
 0.738
glcC
Glc operon transcriptional activator; Identified by similarity to SP:P52072; match to protein family HMM PF00392; match to protein family HMM PF07729.
  
  
 0.685
pdhR
Pyruvate dehydrogenase complex repressor; Identified by similarity to SP:P0ACL9; match to protein family HMM PF00392; match to protein family HMM PF07729.
  
  
 0.679
prpC
2-methylcitrate synthase; Identified by similarity to SP:P31660; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.
  
  
 0.550
prpF
Putative AcnD-accessory protein PrpF; Identified by match to protein family HMM PF04303; match to protein family HMM TIGR02334.
 
  
 0.541
acnD
2-methylisocitrate dehydratase, Fe/S-dependent; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR02333.
 
  
 0.491
PFL_1857
alpha-L-glutamate ligase-related protein; Identified by match to protein family HMM TIGR02291.
       0.480
PFL_1858
Putative membrane protein; Klk.
       0.480
PFL_1859
Conserved hypothetical protein; Identified by match to protein family HMM PF05618.
       0.480
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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