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prpC prpC acnD acnD prpD prpD prpB prpB PFL_3068 PFL_3068 pta pta acnA acnA bkdB bkdB acsA_1 acsA_1 acsA_2 acsA_2 mmsA_1 mmsA_1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
prpC2-methylcitrate synthase; Identified by similarity to SP:P31660; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family. (375 aa)    
Predicted Functional Partners:
acnD
2-methylisocitrate dehydratase, Fe/S-dependent; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR02333.
 
 0.996
prpD
2-methylcitrate dehydratase; Identified by similarity to SP:P77243; match to protein family HMM PF03972; match to protein family HMM TIGR02330.
 
 0.995
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
 
 0.968
PFL_3068
AMP-binding domain protein; Identified by similarity to SP:P39062; match to protein family HMM PF00501.
 
 0.959
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.958
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.953
bkdB
2-oxoisovalerate dehydrogenase E2 component, dihydrolipoamide acyltransferase; Identified by similarity to SP:P09062; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
  
 0.953
acsA_1
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.953
acsA_2
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.953
mmsA_1
Methylmalonate-semialdehyde dehydrogenase (acylating); Identified by similarity to GB:AAA99190.1; match to protein family HMM PF00171; match to protein family HMM TIGR01722.
  
 0.935
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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