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PFL_2464 PFL_2464 PFL_2465 PFL_2465 PFL_2463 PFL_2463 nadC nadC nadA nadA PFL_5821 PFL_5821 PFL_2466 PFL_2466 nadE_1 nadE_1 pncB_1 pncB_1 kptA kptA PFL_1114 PFL_1114
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFL_2464Conserved hypothetical protein. (235 aa)    
Predicted Functional Partners:
PFL_2465
Cytidyltransferase domain protein; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125.
 
   
 0.829
PFL_2463
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
       0.798
nadC
Nicotinate-nucleotide diphosphorylase; Identified by similarity to SP:P30819; match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family.
  
    0.682
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.
  
    0.682
PFL_5821
Conserved hypothetical protein; Identified by match to protein family HMM PF08719; match to protein family HMM TIGR02464.
 
     0.590
PFL_2466
Identified by match to protein family HMM PF00857.
     
 0.571
nadE_1
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
     
 0.545
pncB_1
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
       0.537
kptA
RNA 2'-phosphotransferase, KptA family; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
 
     0.488
PFL_1114
Conserved hypothetical protein.
  
     0.450
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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