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cysI_2 cysI_2 cysH cysH PFL_0863 PFL_0863 cysN cysN cysNC cysNC PFL_3666 PFL_3666 cobA cobA PFL_1287 PFL_1287 cysK cysK metZ metZ mdeA mdeA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cysI_2Sulfite reductase (NADPH) hemoprotein, beta-component; Identified by similarity to GB:AAC46385.1; match to protein family HMM PF01077; match to protein family HMM PF03460. (552 aa)    
Predicted Functional Partners:
cysH
Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
 0.993
PFL_0863
Flavodoxin/oxidoreductase NAD binding domain protein; Identified by match to protein family HMM PF00175; match to protein family HMM PF00258; match to protein family HMM PF03929.
  
 0.989
cysN
Putative sulfate adenylyltransferase, large subunit/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.979
cysNC
Sulfate adenylyltransferase, large subunit/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
  
  
 0.979
PFL_3666
Conserved hypothetical protein; Identified by similarity to GB:AAO56230.1; match to protein family HMM PF06073.
 
  
 0.976
cobA
Siroheme synthase/uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.962
PFL_1287
Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291.
  
 
 0.941
cysK
Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.941
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.931
mdeA
Methionine gamma-lyase; Identified by similarity to GB:CAA04124.1; match to protein family HMM PF01053; match to protein family HMM PF01212.
  
 0.931
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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