node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_3698 | PFL_3699 | PFL_3698 | PFL_3699 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.994 |
PFL_3698 | PFL_3701 | PFL_3698 | PFL_3701 | Conserved hypothetical protein. | Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. | 0.634 |
PFL_3698 | PFL_6269 | PFL_3698 | PFL_6269 | Conserved hypothetical protein. | Hypothetical protein. | 0.609 |
PFL_3698 | dnaE2 | PFL_3698 | PFL_3697 | Conserved hypothetical protein. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.971 |
PFL_3698 | dnaN | PFL_3698 | PFL_0002 | Conserved hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.827 |
PFL_3698 | holB | PFL_3698 | PFL_1802 | Conserved hypothetical protein. | DNA polymerase III, delta' subunit; Identified by match to protein family HMM TIGR00678. | 0.569 |
PFL_3698 | lexA2 | PFL_3698 | PFL_3700 | Conserved hypothetical protein. | Putative LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.886 |
PFL_3698 | polA | PFL_3698 | PFL_0082 | Conserved hypothetical protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.679 |
PFL_3698 | polB | PFL_3698 | PFL_2480 | Conserved hypothetical protein. | DNA polymerase II; Identified by similarity to SP:P21189; match to protein family HMM PF00136; match to protein family HMM PF03104. | 0.817 |
PFL_3698 | recA | PFL_3698 | PFL_1231 | Conserved hypothetical protein. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.637 |
PFL_3699 | PFL_3698 | PFL_3699 | PFL_3698 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.994 |
PFL_3699 | PFL_3701 | PFL_3699 | PFL_3701 | Conserved hypothetical protein. | Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. | 0.634 |
PFL_3699 | dnaE2 | PFL_3699 | PFL_3697 | Conserved hypothetical protein. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.970 |
PFL_3699 | lexA2 | PFL_3699 | PFL_3700 | Conserved hypothetical protein. | Putative LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.866 |
PFL_3701 | PFL_3698 | PFL_3701 | PFL_3698 | Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. | Conserved hypothetical protein. | 0.634 |
PFL_3701 | PFL_3699 | PFL_3701 | PFL_3699 | Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. | Conserved hypothetical protein. | 0.634 |
PFL_3701 | dnaE2 | PFL_3701 | PFL_3697 | Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.625 |
PFL_3701 | lexA2 | PFL_3701 | PFL_3700 | Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. | Putative LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.625 |
PFL_6269 | PFL_3698 | PFL_6269 | PFL_3698 | Hypothetical protein. | Conserved hypothetical protein. | 0.609 |
PFL_6269 | dnaE2 | PFL_6269 | PFL_3697 | Hypothetical protein. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.583 |