node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_4770 | hfq | PFL_4770 | PFL_0566 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.463 |
PFL_4770 | pnp | PFL_4770 | PFL_0848 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.607 |
PFL_4770 | rne | PFL_4770 | PFL_1787 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.414 |
PFL_4770 | rnr | PFL_4770 | PFL_0577 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.456 |
PFL_4770 | rplO | PFL_4770 | PFL_5563 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.424 |
PFL_4770 | rpmE_2 | PFL_4770 | PFL_0441 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | Ribosomal protein L31; Binds the 23S rRNA. | 0.424 |
PFL_4770 | rpmJ | PFL_4770 | PFL_3806 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | Ribosomal protein L36; Identified by match to protein family HMM PF00444; match to protein family HMM TIGR01022; Belongs to the bacterial ribosomal protein bL36 family. | 0.448 |
PFL_4770 | rppH | PFL_4770 | PFL_5900 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.416 |
PFL_4770 | rpsL | PFL_4770 | PFL_5587 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.487 |
PFL_4770 | rpsQ | PFL_4770 | PFL_5573 | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.435 |
hfq | PFL_4770 | PFL_0566 | PFL_4770 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | 0.463 |
hfq | pnp | PFL_0566 | PFL_0848 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.817 |
hfq | rne | PFL_0566 | PFL_1787 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.729 |
hfq | rnr | PFL_0566 | PFL_0577 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.622 |
hfq | rppH | PFL_0566 | PFL_5900 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.631 |
hfq | rpsL | PFL_0566 | PFL_5587 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.531 |
pnp | PFL_4770 | PFL_0848 | PFL_4770 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Cold-shock DNA-binding domain protein; Identified by match to protein family HMM PF00313. | 0.607 |
pnp | hfq | PFL_0848 | PFL_0566 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.817 |
pnp | rne | PFL_0848 | PFL_1787 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.887 |
pnp | rnr | PFL_0848 | PFL_0577 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.795 |