node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_4845 | PFL_4849 | PFL_4845 | PFL_4849 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | 0.993 |
PFL_4845 | nth | PFL_4845 | PFL_4850 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.812 |
PFL_4845 | rnfB | PFL_4845 | PFL_4846 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | 0.986 |
PFL_4845 | rnfD | PFL_4845 | PFL_4847 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | 0.991 |
PFL_4845 | rnfG | PFL_4845 | PFL_4848 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | 0.989 |
PFL_4849 | PFL_4845 | PFL_4849 | PFL_4845 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | 0.993 |
PFL_4849 | nth | PFL_4849 | PFL_4850 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.940 |
PFL_4849 | rnfB | PFL_4849 | PFL_4846 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. | 0.975 |
PFL_4849 | rnfD | PFL_4849 | PFL_4847 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. | 0.996 |
PFL_4849 | rnfG | PFL_4849 | PFL_4848 | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. | 0.996 |
PFL_6057 | nth | PFL_6057 | PFL_4850 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.916 |
PFL_6057 | polA | PFL_6057 | PFL_0082 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.839 |
PFL_6057 | ung | PFL_6057 | PFL_1435 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.699 |
PFL_6057 | xth | PFL_6057 | PFL_3928 | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.919 |
mutM | nth | PFL_5870 | PFL_4850 | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.721 |
mutM | polA | PFL_5870 | PFL_0082 | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.979 |
mutM | ung | PFL_5870 | PFL_1435 | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.408 |
nth | PFL_4845 | PFL_4850 | PFL_4845 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | 0.812 |
nth | PFL_4849 | PFL_4850 | PFL_4849 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative membrane protein; Belongs to the NqrDE/RnfAE family. | 0.940 |
nth | PFL_6057 | PFL_4850 | PFL_6057 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Putative exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00633. | 0.916 |