node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_0296 | PFL_0994 | PFL_0296 | PFL_0994 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 0.910 |
PFL_0296 | PFL_2451 | PFL_0296 | PFL_2451 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | 0.918 |
PFL_0296 | adk | PFL_0296 | PFL_1148 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.906 |
PFL_0296 | amn | PFL_0296 | PFL_5424 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.905 |
PFL_0296 | apt | PFL_0296 | PFL_1909 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.907 |
PFL_0296 | icc | PFL_0296 | PFL_0543 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.901 |
PFL_0296 | purB | PFL_0296 | PFL_3893 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Adenylosuccinate lyase; Identified by similarity to SP:P25739; match to protein family HMM PF00206; match to protein family HMM PF08328; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.901 |
PFL_0296 | rihA | PFL_0296 | PFL_2107 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by similarity to SP:P41409; match to protein family HMM PF01156; Belongs to the IUNH family. | 0.911 |
PFL_0296 | surE | PFL_0296 | PFL_1204 | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.922 |
PFL_0994 | PFL_0296 | PFL_0994 | PFL_0296 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | 0.910 |
PFL_0994 | PFL_2451 | PFL_0994 | PFL_2451 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | 0.900 |
PFL_0994 | add | PFL_0994 | PFL_0719 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.636 |
PFL_0994 | adk | PFL_0994 | PFL_1148 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.906 |
PFL_0994 | amn | PFL_0994 | PFL_5424 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.900 |
PFL_0994 | apt | PFL_0994 | PFL_1909 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.918 |
PFL_0994 | icc | PFL_0994 | PFL_0543 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.917 |
PFL_0994 | purB | PFL_0994 | PFL_3893 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenylosuccinate lyase; Identified by similarity to SP:P25739; match to protein family HMM PF00206; match to protein family HMM PF08328; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.915 |
PFL_0994 | rihA | PFL_0994 | PFL_2107 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by similarity to SP:P41409; match to protein family HMM PF01156; Belongs to the IUNH family. | 0.911 |
PFL_0994 | surE | PFL_0994 | PFL_1204 | Ser/Thr protein phosphatase/5'-nucleotidase domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.921 |
PFL_2451 | PFL_0296 | PFL_2451 | PFL_0296 | Conserved hypothetical protein; Identified by similarity to SP:P0ADR8; match to protein family HMM PF03641. | HAD-superfamily hydrolase, subfamily IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509. | 0.918 |