node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_3873 | pabB | PFL_3873 | PFL_1856 | Putative glycosyltransferase; Identified by match to protein family HMM PF02885. | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | 0.912 |
PFL_3873 | trpA | PFL_3873 | PFL_0036 | Putative glycosyltransferase; Identified by match to protein family HMM PF02885. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.869 |
PFL_3873 | trpB | PFL_3873 | PFL_0037 | Putative glycosyltransferase; Identified by match to protein family HMM PF02885. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.861 |
PFL_3873 | trpC | PFL_3873 | PFL_5621 | Putative glycosyltransferase; Identified by match to protein family HMM PF02885. | Indole-3-glycerol phosphate synthase; Identified by similarity to SP:P20577; match to protein family HMM PF00218; Belongs to the TrpC family. | 0.882 |
PFL_3873 | trpE | PFL_3873 | PFL_5629 | Putative glycosyltransferase; Identified by match to protein family HMM PF02885. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.907 |
PFL_3873 | trpF | PFL_3873 | PFL_2072 | Putative glycosyltransferase; Identified by match to protein family HMM PF02885. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.879 |
PFL_3873 | trpG | PFL_3873 | PFL_5623 | Putative glycosyltransferase; Identified by match to protein family HMM PF02885. | Anthranilate synthase, component II; Identified by similarity to PIR:A01122; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.859 |
PFL_5620 | trpC | PFL_5620 | PFL_5621 | Conserved hypothetical protein. | Indole-3-glycerol phosphate synthase; Identified by similarity to SP:P20577; match to protein family HMM PF00218; Belongs to the TrpC family. | 0.735 |
PFL_5620 | trpD | PFL_5620 | PFL_5622 | Conserved hypothetical protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.735 |
PFL_5620 | trpG | PFL_5620 | PFL_5623 | Conserved hypothetical protein. | Anthranilate synthase, component II; Identified by similarity to PIR:A01122; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.735 |
pabB | PFL_3873 | PFL_1856 | PFL_3873 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | Putative glycosyltransferase; Identified by match to protein family HMM PF02885. | 0.912 |
pabB | pchA | PFL_1856 | PFL_3488 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | Isochorismate synthase PchA; Previously identified and characterized. See Youard et al 2007 (PMID: 17938167) for more information; identified by similarity to GB:ABW70804.1; match to protein family HMM PF00425; match to protein family HMM TIGR00543. | 0.419 |
pabB | trpA | PFL_1856 | PFL_0036 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.939 |
pabB | trpB | PFL_1856 | PFL_0037 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.951 |
pabB | trpC | PFL_1856 | PFL_5621 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | Indole-3-glycerol phosphate synthase; Identified by similarity to SP:P20577; match to protein family HMM PF00218; Belongs to the TrpC family. | 0.985 |
pabB | trpD | PFL_1856 | PFL_5622 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.973 |
pabB | trpE | PFL_1856 | PFL_5629 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.848 |
pabB | trpF | PFL_1856 | PFL_2072 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family. | 0.944 |
pabB | trpG | PFL_1856 | PFL_5623 | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | Anthranilate synthase, component II; Identified by similarity to PIR:A01122; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.999 |
pchA | pabB | PFL_3488 | PFL_1856 | Isochorismate synthase PchA; Previously identified and characterized. See Youard et al 2007 (PMID: 17938167) for more information; identified by similarity to GB:ABW70804.1; match to protein family HMM PF00425; match to protein family HMM TIGR00543. | Aminodeoxychorismate synthase, component I; Identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553. | 0.419 |