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pqqF pqqF pqqB_2 pqqB_2 pqqC pqqC pqqD pqqD PFL_5671 PFL_5671 pqqE pqqE pqqB_1 pqqB_1 PFL_0316 PFL_0316 pqqA_1 pqqA_1 PFL_0863 PFL_0863 pqqM pqqM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pqqFCoenzyme PQQ biosynthesis protein PqqF; Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; match to protein family HMM TIGR02110; Belongs to the peptidase M16 family. (820 aa)    
Predicted Functional Partners:
pqqB_2
Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
     
 0.740
pqqC
Coenzyme PQQ biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
     
 0.720
pqqD
Coenzyme PQQ synthesis protein D; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
     
 0.698
PFL_5671
Identified by match to protein family HMM PF00795.
   
 
 0.658
pqqE
Coenzyme PQQ biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
     
 0.626
pqqB_1
Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
     
 0.624
PFL_0316
Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719.
   
 
 0.531
pqqA_1
Coenzyme PQQ synthesis protein A; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide; Belongs to the PqqA family.
       0.521
PFL_0863
Flavodoxin/oxidoreductase NAD binding domain protein; Identified by match to protein family HMM PF00175; match to protein family HMM PF00258; match to protein family HMM PF03929.
   
 
  0.515
pqqM
Peptidase, S9A/B/C family, catalytic domain protein; Identified by match to protein family HMM PF00326.
  
  
 0.497
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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