node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_1412 | proC | PFL_1412 | PFL_5839 | Proline racemase family protein; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.923 |
PFL_5838 | PFL_5840 | PFL_5838 | PFL_5840 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Identified by match to protein family HMM PF02325. | 0.895 |
PFL_5838 | PFL_5841 | PFL_5838 | PFL_5841 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | 0.763 |
PFL_5838 | proC | PFL_5838 | PFL_5839 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.838 |
PFL_5840 | PFL_5838 | PFL_5840 | PFL_5838 | Identified by match to protein family HMM PF02325. | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.895 |
PFL_5840 | PFL_5841 | PFL_5840 | PFL_5841 | Identified by match to protein family HMM PF02325. | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | 0.857 |
PFL_5840 | proC | PFL_5840 | PFL_5839 | Identified by match to protein family HMM PF02325. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.851 |
PFL_5841 | PFL_5838 | PFL_5841 | PFL_5838 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.763 |
PFL_5841 | PFL_5840 | PFL_5841 | PFL_5840 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Identified by match to protein family HMM PF02325. | 0.857 |
PFL_5841 | proC | PFL_5841 | PFL_5839 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.796 |
arcB | pip | PFL_3641 | PFL_0411 | Ornithine cyclodeaminase; Identified by similarity to SP:P09773; match to protein family HMM PF02423. | Prolyl aminopeptidase; Identified by match to protein family HMM PF00561; match to protein family HMM TIGR01249; Belongs to the peptidase S33 family. | 0.900 |
arcB | proC | PFL_3641 | PFL_5839 | Ornithine cyclodeaminase; Identified by similarity to SP:P09773; match to protein family HMM PF02423. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.921 |
arcB | putA | PFL_3641 | PFL_0495 | Ornithine cyclodeaminase; Identified by similarity to SP:P09773; match to protein family HMM PF02423. | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.953 |
pip | arcB | PFL_0411 | PFL_3641 | Prolyl aminopeptidase; Identified by match to protein family HMM PF00561; match to protein family HMM TIGR01249; Belongs to the peptidase S33 family. | Ornithine cyclodeaminase; Identified by similarity to SP:P09773; match to protein family HMM PF02423. | 0.900 |
pip | proC | PFL_0411 | PFL_5839 | Prolyl aminopeptidase; Identified by match to protein family HMM PF00561; match to protein family HMM TIGR01249; Belongs to the peptidase S33 family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.904 |
pip | putA | PFL_0411 | PFL_0495 | Prolyl aminopeptidase; Identified by match to protein family HMM PF00561; match to protein family HMM TIGR01249; Belongs to the peptidase S33 family. | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.900 |
proA | proB | PFL_5456 | PFL_5326 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.999 |
proA | proC | PFL_5456 | PFL_5839 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.763 |
proA | putA | PFL_5456 | PFL_0495 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.953 |
proB | proA | PFL_5326 | PFL_5456 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.999 |