STRINGSTRING
metX metX metW metW cysD cysD hom hom metZ metZ mdeA mdeA PFL_3809 PFL_3809 PFL_3341 PFL_3341 ilvA_1 ilvA_1 PFL_3440 PFL_3440 ilvA_2 ilvA_2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
metXHomoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (379 aa)    
Predicted Functional Partners:
metW
Methionine biosynthesis protein; Identified by match to protein family HMM PF07021; match to protein family HMM PF08241; match to protein family HMM TIGR02081.
  
 0.997
cysD
O-acetylhomoserine sulfhydrylase; Identified by similarity to SP:O13326; match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM TIGR01326.
 
 
 0.980
hom
Homoserine dehydrogenase; Identified by similarity to SP:P29365; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.
 
 0.965
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
  
 0.956
mdeA
Methionine gamma-lyase; Identified by similarity to GB:CAA04124.1; match to protein family HMM PF01053; match to protein family HMM PF01212.
 
  
 0.941
PFL_3809
Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.
 
 0.939
PFL_3341
Identified by match to protein family HMM PF00561; Belongs to the AB hydrolase superfamily. MetX family.
  
  
 
0.928
ilvA_1
Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.822
PFL_3440
Identified by match to protein family HMM PF00291.
  
 
 0.822
ilvA_2
Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.822
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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