STRINGSTRING
PFL_5844 PFL_5844 metW metW rdgB rdgB PFL_5846 PFL_5846 PFL_5847 PFL_5847 metX metX PFL_1916 PFL_1916 PFL_6034 PFL_6034 PFL_0339 PFL_0339 PFL_4439 PFL_4439 PFL_4442 PFL_4442
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFL_5844Conserved hypothetical protein. (144 aa)    
Predicted Functional Partners:
metW
Methionine biosynthesis protein; Identified by match to protein family HMM PF07021; match to protein family HMM PF08241; match to protein family HMM TIGR02081.
      0.910
rdgB
Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
    0.897
PFL_5846
Putative coproporphyrinogen dehydrogenase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.802
PFL_5847
Conserved hypothetical protein.
       0.792
metX
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
       0.710
PFL_1916
Conserved hypothetical protein.
  
     0.674
PFL_6034
Putative cytochrome c5; Identified by similarity to SP:P11732.
  
     0.665
PFL_0339
Conserved hypothetical protein.
  
     0.615
PFL_4439
Conserved hypothetical protein.
  
     0.596
PFL_4442
Conserved hypothetical protein.
  
     0.557
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.