node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PFL_5840 | PFL_5841 | PFL_5840 | PFL_5841 | Identified by match to protein family HMM PF02325. | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | 0.857 |
PFL_5840 | PFL_5844 | PFL_5840 | PFL_5844 | Identified by match to protein family HMM PF02325. | Conserved hypothetical protein. | 0.549 |
PFL_5840 | PFL_5846 | PFL_5840 | PFL_5846 | Identified by match to protein family HMM PF02325. | Putative coproporphyrinogen dehydrogenase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.479 |
PFL_5840 | PFL_5847 | PFL_5840 | PFL_5847 | Identified by match to protein family HMM PF02325. | Conserved hypothetical protein. | 0.412 |
PFL_5840 | metW | PFL_5840 | PFL_5843 | Identified by match to protein family HMM PF02325. | Methionine biosynthesis protein; Identified by match to protein family HMM PF07021; match to protein family HMM PF08241; match to protein family HMM TIGR02081. | 0.516 |
PFL_5840 | metX | PFL_5840 | PFL_5842 | Identified by match to protein family HMM PF02325. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.489 |
PFL_5840 | proC | PFL_5840 | PFL_5839 | Identified by match to protein family HMM PF02325. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.851 |
PFL_5840 | rdgB | PFL_5840 | PFL_5845 | Identified by match to protein family HMM PF02325. | Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.498 |
PFL_5841 | PFL_5840 | PFL_5841 | PFL_5840 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Identified by match to protein family HMM PF02325. | 0.857 |
PFL_5841 | PFL_5844 | PFL_5841 | PFL_5844 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Conserved hypothetical protein. | 0.493 |
PFL_5841 | PFL_5846 | PFL_5841 | PFL_5846 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Putative coproporphyrinogen dehydrogenase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.493 |
PFL_5841 | PFL_5847 | PFL_5841 | PFL_5847 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Conserved hypothetical protein. | 0.489 |
PFL_5841 | metW | PFL_5841 | PFL_5843 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Methionine biosynthesis protein; Identified by match to protein family HMM PF07021; match to protein family HMM PF08241; match to protein family HMM TIGR02081. | 0.533 |
PFL_5841 | metX | PFL_5841 | PFL_5842 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.507 |
PFL_5841 | proC | PFL_5841 | PFL_5839 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.796 |
PFL_5841 | rdgB | PFL_5841 | PFL_5845 | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.493 |
PFL_5844 | PFL_5840 | PFL_5844 | PFL_5840 | Conserved hypothetical protein. | Identified by match to protein family HMM PF02325. | 0.549 |
PFL_5844 | PFL_5841 | PFL_5844 | PFL_5841 | Conserved hypothetical protein. | Conserved hypothetical protein; Identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251; Belongs to the UPF0235 family. | 0.493 |
PFL_5844 | PFL_5846 | PFL_5844 | PFL_5846 | Conserved hypothetical protein. | Putative coproporphyrinogen dehydrogenase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.802 |
PFL_5844 | PFL_5847 | PFL_5844 | PFL_5847 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.792 |