STRINGSTRING
ubiA ubiA ubiC ubiC ubiD ubiD ubiX ubiX PFL_5330 PFL_5330 ybgC ybgC PFL_5541 PFL_5541 ubiG ubiG PFL_5965 PFL_5965 ubiH ubiH rubA rubA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiA4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (296 aa)    
Predicted Functional Partners:
ubiC
Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
    
 0.986
ubiD
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
 
  
 0.963
ubiX
Polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylase family protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
  
 0.961
PFL_5330
Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
 
 
 0.916
ybgC
Tol-Pal system-associated acyl-CoA thioesterase; Identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051; match to protein family HMM TIGR02799.
     
 0.904
PFL_5541
Prenyltransferase, UbiA family; Identified by match to protein family HMM PF01040.
     
  0.900
ubiG
3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.803
PFL_5965
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; Identified by similarity to SP:P75728; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988.
  
   
 0.750
ubiH
2-polyprenyl-6-methoxyphenol 4-hydroxylase; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988.
  
   
 0.733
rubA
Rubredoxin; Identified by similarity to SP:P00268; match to protein family HMM PF00301.
     
 0.638
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.