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dksA-2 dksA-2 PFL_6173 PFL_6173 PFL_6172 PFL_6172 rpoZ rpoZ rpoC rpoC rpoB rpoB PFL_6171 PFL_6171 hfq hfq PFL_6175 PFL_6175 rplK rplK yjiA yjiA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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dksA-2Putative RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. (134 aa)    
Predicted Functional Partners:
PFL_6173
Identified by match to protein family HMM PF02492; match to protein family HMM PF07683.
  
  
 0.864
PFL_6172
Conserved hypothetical protein; Identified by match to protein family HMM PF08856.
  
    0.832
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.754
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.720
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.645
PFL_6171
Cobalamin synthesis protein/P47K family protein; Identified by match to protein family HMM PF02492.
  
  
 0.635
hfq
RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.600
PFL_6175
Conserved hypothetical protein.
  
    0.592
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
  
 0.583
yjiA
GTP-binding protein, YjiA family; Identified by similarity to SP:P24203; match to protein family HMM PF02492; match to protein family HMM PF07683.
  
  
 0.567
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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