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glmU glmU glmM glmM glmS glmS murA murA wecB wecB wbjD wbjD prs prs PFL_5645 PFL_5645 wbpM wbpM wbjB wbjB lpxA lpxA
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the trans [...] (455 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.978
glmS
Glutamine-fructose-6-phosphate transaminase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 0.957
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
 
 0.953
wecB
UDP-N-acetylglucosamine 2-epimerase; Identified by similarity to SP:P27828; match to protein family HMM PF02350; match to protein family HMM TIGR00236; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
  
 0.936
wbjD
UDP-2-acetamido-2,6-dideoxy-beta-L-talose 2-epimerase WbjD; See Kneidinger et. al. 2003 (PMID: 12464616) for more information; identified by similarity to GB:AAD45267.1; match to protein family HMM PF02350; match to protein family HMM TIGR00236; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
    
 0.924
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
  
 0.924
PFL_5645
Putative aminoglycoside phosphotransferase; Identified by similarity to GB:AAV66960.1; match to protein family HMM PF01636.
    
 0.922
wbpM
Nucleotide sugar epimerase/dehydratase WbpM; Identified by similarity to GB:AAF72960.1; match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993.
    
 0.921
wbjB
Trifunctional UDP-D-GlcNAc 4,6-dehydratase/5-epimerase/3-epimerase WbjB; See Kneidinger et. al. 2003 (PMID: 12464616) for more information; identified by similarity to GB:AAD45265.1; match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM PF08485.
    
 0.921
lpxA
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
 
 0.874
Your Current Organism:
Pseudomonas protegens
NCBI taxonomy Id: 220664
Other names: P. protegens Pf-5, Pseudomonas fluorescens Pf-5, Pseudomonas protegens Pf-5, Pseudomonas protegens str. Pf-5, Pseudomonas protegens strain Pf-5, Pseudomonas sp. Pf-5
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