node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEA66924.1 | AEA67963.1 | PSEBR_a762 | PSEBR_a1752 | DNA repair protein; May be involved in recombinational repair of damaged DNA. | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.840 |
AEA66924.1 | AEA68153.1 | PSEBR_a762 | PSEBR_a1930 | DNA repair protein; May be involved in recombinational repair of damaged DNA. | ImuA protein. | 0.469 |
AEA66924.1 | AEA68154.1 | PSEBR_a762 | PSEBR_a1931 | DNA repair protein; May be involved in recombinational repair of damaged DNA. | ImuB protein. | 0.511 |
AEA66924.1 | AEA71103.1 | PSEBR_a762 | PSEBR_a4685 | DNA repair protein; May be involved in recombinational repair of damaged DNA. | Conserved hypothetical protein. | 0.559 |
AEA66924.1 | dinB | PSEBR_a762 | PSEBR_a1140 | DNA repair protein; May be involved in recombinational repair of damaged DNA. | DNA-directed DNA polymerase (DNA polymerase IV); Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.614 |
AEA66924.1 | lexA | PSEBR_a762 | PSEBR_a1753 | DNA repair protein; May be involved in recombinational repair of damaged DNA. | Putative transcription factor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.689 |
AEA66924.1 | polA | PSEBR_a762 | PSEBR_a40 | DNA repair protein; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.624 |
AEA66924.1 | recA | PSEBR_a762 | PSEBR_a1123 | DNA repair protein; May be involved in recombinational repair of damaged DNA. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.855 |
AEA67963.1 | AEA66924.1 | PSEBR_a1752 | PSEBR_a762 | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.840 |
AEA67963.1 | AEA67965.1 | PSEBR_a1752 | PSEBR_a1754 | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Transcriptional regulator. | 0.546 |
AEA67963.1 | AEA68154.1 | PSEBR_a1752 | PSEBR_a1931 | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | ImuB protein. | 0.441 |
AEA67963.1 | AEA71103.1 | PSEBR_a1752 | PSEBR_a4685 | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Conserved hypothetical protein. | 0.892 |
AEA67963.1 | dinB | PSEBR_a1752 | PSEBR_a1140 | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | DNA-directed DNA polymerase (DNA polymerase IV); Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.434 |
AEA67963.1 | lexA | PSEBR_a1752 | PSEBR_a1753 | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Putative transcription factor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.905 |
AEA67963.1 | recA | PSEBR_a1752 | PSEBR_a1123 | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.573 |
AEA67965.1 | AEA67963.1 | PSEBR_a1754 | PSEBR_a1752 | Transcriptional regulator. | Putative cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 0.546 |
AEA67965.1 | lexA | PSEBR_a1754 | PSEBR_a1753 | Transcriptional regulator. | Putative transcription factor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.554 |
AEA68153.1 | AEA66924.1 | PSEBR_a1930 | PSEBR_a762 | ImuA protein. | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.469 |
AEA68153.1 | AEA68154.1 | PSEBR_a1930 | PSEBR_a1931 | ImuA protein. | ImuB protein. | 0.994 |
AEA68153.1 | dinB | PSEBR_a1930 | PSEBR_a1140 | ImuA protein. | DNA-directed DNA polymerase (DNA polymerase IV); Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.872 |