STRINGSTRING
AEA69624.1 AEA69624.1 AEA69910.1 AEA69910.1 AEA70550.1 AEA70550.1 AEA69911.1 AEA69911.1 AEA67944.1 AEA67944.1 prpB prpB AEA69919.1 AEA69919.1 AEA70350.1 AEA70350.1 AEA70352.1 AEA70352.1 sucC sucC AEA70545.1 AEA70545.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEA69624.1Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (869 aa)    
Predicted Functional Partners:
AEA69910.1
Isocitrate dehydrogenase (NADP(+)).
  
 
 0.984
AEA70550.1
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.979
AEA69911.1
Isocitrate dehydrogenase (NADP(+)); Belongs to the monomeric-type IDH family.
 
 
 0.956
AEA67944.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.935
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.923
AEA69919.1
Isocitrate lyase.
     
 0.922
AEA70350.1
Conserved hypothetical protein.
    
 0.914
AEA70352.1
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 
 0.898
sucC
Succinate--CoA ligase (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.877
AEA70545.1
2-oxoglutarate dehydrogenase E1 component.
   
  
 0.870
Your Current Organism:
Pseudomonas brassicacearum
NCBI taxonomy Id: 994484
Other names: P. brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum CFBP 11874, Pseudomonas brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum str. NFM421, Pseudomonas brassicacearum subsp. brassicacearum strain NFM421
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.