STRINGSTRING
AEA70352.1 AEA70352.1 AEA70351.1 AEA70351.1 AEA67944.1 AEA67944.1 prpB prpB AEA71141.1 AEA71141.1 AEA69702.1 AEA69702.1 AEA69241.1 AEA69241.1 acsA acsA acsA-2 acsA-2 AEA69673.1 AEA69673.1 AEA66829.1 AEA66829.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEA70352.12-methylcitrate synthase; Belongs to the citrate synthase family. (375 aa)    
Predicted Functional Partners:
AEA70351.1
Aconitate hydratase.
 
 0.997
AEA67944.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.964
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
 
 0.962
AEA71141.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.961
AEA69702.1
Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex).
  
 0.954
AEA69241.1
Putative AMP-binding protein.
  
 0.948
acsA
Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.948
acsA-2
Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.948
AEA69673.1
Methylmalonate-semialdehyde dehydrogenase (acylating).
  
 0.932
AEA66829.1
Methylmalonate-semialdehyde dehydrogenase (acylating).
  
 0.932
Your Current Organism:
Pseudomonas brassicacearum
NCBI taxonomy Id: 994484
Other names: P. brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum CFBP 11874, Pseudomonas brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum str. NFM421, Pseudomonas brassicacearum subsp. brassicacearum strain NFM421
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