node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEA69241.1 | AEA70352.1 | PSEBR_a2939 | PSEBR_a3957 | Putative AMP-binding protein. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.948 |
AEA69241.1 | acsA | PSEBR_a2939 | PSEBR_a4325 | Putative AMP-binding protein. | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.923 |
AEA69241.1 | acsA-2 | PSEBR_a2939 | PSEBR_a4820 | Putative AMP-binding protein. | Acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.921 |
AEA69241.1 | glcB | PSEBR_a2939 | PSEBR_a5188 | Putative AMP-binding protein. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.948 |
AEA69241.1 | prpB | PSEBR_a2939 | PSEBR_a3958 | Putative AMP-binding protein. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.871 |
AEA69241.1 | sucC | PSEBR_a2939 | PSEBR_a4137 | Putative AMP-binding protein. | Succinate--CoA ligase (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.843 |
AEA69241.1 | sucD | PSEBR_a2939 | PSEBR_a4136 | Putative AMP-binding protein. | Succinate--CoA ligase (GDP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.834 |
AEA69624.1 | AEA70350.1 | PSEBR_a3308 | PSEBR_a3955 | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Conserved hypothetical protein. | 0.914 |
AEA69624.1 | AEA70352.1 | PSEBR_a3308 | PSEBR_a3957 | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.898 |
AEA69624.1 | prpB | PSEBR_a3308 | PSEBR_a3958 | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.923 |
AEA69624.1 | sucC | PSEBR_a3308 | PSEBR_a4137 | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Succinate--CoA ligase (ADP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.877 |
AEA69624.1 | sucD | PSEBR_a3308 | PSEBR_a4136 | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | Succinate--CoA ligase (GDP-forming); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.541 |
AEA70350.1 | AEA69624.1 | PSEBR_a3955 | PSEBR_a3308 | Conserved hypothetical protein. | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | 0.914 |
AEA70350.1 | AEA70352.1 | PSEBR_a3955 | PSEBR_a3957 | Conserved hypothetical protein. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.915 |
AEA70350.1 | AEA70354.1 | PSEBR_a3955 | PSEBR_a3959 | Conserved hypothetical protein. | Putative Transcription factor, GntR family. | 0.593 |
AEA70350.1 | prpB | PSEBR_a3955 | PSEBR_a3958 | Conserved hypothetical protein. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.845 |
AEA70352.1 | AEA69241.1 | PSEBR_a3957 | PSEBR_a2939 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Putative AMP-binding protein. | 0.948 |
AEA70352.1 | AEA69624.1 | PSEBR_a3957 | PSEBR_a3308 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Aconitate hydratase; Belongs to the aconitase/IPM isomerase family. | 0.898 |
AEA70352.1 | AEA70350.1 | PSEBR_a3957 | PSEBR_a3955 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Conserved hypothetical protein. | 0.915 |
AEA70352.1 | AEA70354.1 | PSEBR_a3957 | PSEBR_a3959 | 2-methylcitrate synthase; Belongs to the citrate synthase family. | Putative Transcription factor, GntR family. | 0.617 |