STRINGSTRING
AEA70564.1 AEA70564.1 eno eno pgi pgi AEA70563.1 AEA70563.1 AEA72127.1 AEA72127.1 AEA66563.1 AEA66563.1 gmk gmk AEA70671.1 AEA70671.1 adk adk tpiA tpiA AEA67883.1 AEA67883.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEA70564.1Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase (enolase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
 0.989
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.977
AEA70563.1
Putative hydroxypyruvate reductase.
 
 
 0.972
AEA72127.1
Oxaloacetate decarboxylase, alpha chain.
  
 
 0.949
AEA66563.1
Putative malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
  
 0.948
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.938
AEA70671.1
Putative D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.929
adk
Putative Nucleoside-triphosphate--adenylate kinase (Putative adenylate kinase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.928
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.926
AEA67883.1
Pyruvate, water dikinase (phosphoenolpyruvate synthase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.923
Your Current Organism:
Pseudomonas brassicacearum
NCBI taxonomy Id: 994484
Other names: P. brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum CFBP 11874, Pseudomonas brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum str. NFM421, Pseudomonas brassicacearum subsp. brassicacearum strain NFM421
Server load: low (12%) [HD]