STRINGSTRING
AEA70894.1 AEA70894.1 eno eno pgi pgi AEA72127.1 AEA72127.1 AEA66563.1 AEA66563.1 gmk gmk AEA70671.1 AEA70671.1 adk adk AEA67883.1 AEA67883.1 pckA pckA ppc ppc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEA70894.1Pyruvate kinase; Belongs to the pyruvate kinase family. (483 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase (enolase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
 0.988
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.978
AEA72127.1
Oxaloacetate decarboxylase, alpha chain.
  
 
 0.949
AEA66563.1
Putative malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
  
 0.948
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.934
AEA70671.1
Putative D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.929
adk
Putative Nucleoside-triphosphate--adenylate kinase (Putative adenylate kinase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.928
AEA67883.1
Pyruvate, water dikinase (phosphoenolpyruvate synthase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.923
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
    
 0.923
ppc
Putative Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.922
Your Current Organism:
Pseudomonas brassicacearum
NCBI taxonomy Id: 994484
Other names: P. brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum CFBP 11874, Pseudomonas brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum str. NFM421, Pseudomonas brassicacearum subsp. brassicacearum strain NFM421
Server load: low (16%) [HD]