node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEA68492.1 | AEA70831.1 | PSEBR_a2219 | PSEBR_a4422 | Putative aminomethyltransferase; Belongs to the GcvT family. | Aminomethyltransferase. | 0.923 |
AEA68492.1 | folD | PSEBR_a2219 | PSEBR_a1812 | Putative aminomethyltransferase; Belongs to the GcvT family. | Putative bifunctional protein: Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.937 |
AEA68492.1 | folD-2 | PSEBR_a2219 | PSEBR_a2209 | Putative aminomethyltransferase; Belongs to the GcvT family. | Putative bifunctional protein: methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.937 |
AEA68492.1 | folD-3 | PSEBR_a2219 | PSEBR_a2217 | Putative aminomethyltransferase; Belongs to the GcvT family. | Putative bifunctional protein: Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.966 |
AEA68492.1 | gcvP | PSEBR_a2219 | PSEBR_a4420 | Putative aminomethyltransferase; Belongs to the GcvT family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.998 |
AEA68492.1 | gcvT | PSEBR_a2219 | PSEBR_a5427 | Putative aminomethyltransferase; Belongs to the GcvT family. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.921 |
AEA68492.1 | glyA-4 | PSEBR_a2219 | PSEBR_a5215 | Putative aminomethyltransferase; Belongs to the GcvT family. | Glycine hydroxymethyltransferase (serine hydroxymethyltransferase); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.941 |
AEA68492.1 | purH | PSEBR_a2219 | PSEBR_a627 | Putative aminomethyltransferase; Belongs to the GcvT family. | Bifunctional protein: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | 0.926 |
AEA68492.1 | purN | PSEBR_a2219 | PSEBR_a4254 | Putative aminomethyltransferase; Belongs to the GcvT family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.916 |
AEA70831.1 | AEA68492.1 | PSEBR_a4422 | PSEBR_a2219 | Aminomethyltransferase. | Putative aminomethyltransferase; Belongs to the GcvT family. | 0.923 |
AEA70831.1 | folD | PSEBR_a4422 | PSEBR_a1812 | Aminomethyltransferase. | Putative bifunctional protein: Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.933 |
AEA70831.1 | folD-2 | PSEBR_a4422 | PSEBR_a2209 | Aminomethyltransferase. | Putative bifunctional protein: methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.933 |
AEA70831.1 | folD-3 | PSEBR_a4422 | PSEBR_a2217 | Aminomethyltransferase. | Putative bifunctional protein: Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.933 |
AEA70831.1 | gcvP | PSEBR_a4422 | PSEBR_a4420 | Aminomethyltransferase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
AEA70831.1 | gcvT | PSEBR_a4422 | PSEBR_a5427 | Aminomethyltransferase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.917 |
AEA70831.1 | glyA-4 | PSEBR_a4422 | PSEBR_a5215 | Aminomethyltransferase. | Glycine hydroxymethyltransferase (serine hydroxymethyltransferase); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.959 |
AEA70831.1 | purH | PSEBR_a4422 | PSEBR_a627 | Aminomethyltransferase. | Bifunctional protein: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase. | 0.926 |
AEA70831.1 | purN | PSEBR_a4422 | PSEBR_a4254 | Aminomethyltransferase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.916 |
AEA71690.1 | folD | PSEBR_a5212 | PSEBR_a1812 | Sarcosine oxidase, alpha subunit; Belongs to the GcvT family. | Putative bifunctional protein: Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.500 |
AEA71690.1 | folD-2 | PSEBR_a5212 | PSEBR_a2209 | Sarcosine oxidase, alpha subunit; Belongs to the GcvT family. | Putative bifunctional protein: methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.500 |