node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEA67839.1 | AEA68169.1 | PSEBR_a1635 | PSEBR_a1946 | Conserved hypothetical protein, GAF domain-containing protein. | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.900 |
AEA67839.1 | AEA70268.1 | PSEBR_a1635 | PSEBR_a3878 | Conserved hypothetical protein, GAF domain-containing protein. | Aspartate transaminase (Aspartate aminotransferase). | 0.908 |
AEA67839.1 | metE | PSEBR_a1635 | PSEBR_a4505 | Conserved hypothetical protein, GAF domain-containing protein. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.900 |
AEA67839.1 | metK | PSEBR_a1635 | PSEBR_a5272 | Conserved hypothetical protein, GAF domain-containing protein. | Putative S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.901 |
AEA68169.1 | AEA67839.1 | PSEBR_a1946 | PSEBR_a1635 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Conserved hypothetical protein, GAF domain-containing protein. | 0.900 |
AEA68169.1 | AEA70268.1 | PSEBR_a1946 | PSEBR_a3878 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate transaminase (Aspartate aminotransferase). | 0.922 |
AEA68169.1 | AEA71767.1 | PSEBR_a1946 | PSEBR_a5271 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative Transcription factor, ArsR family. | 0.522 |
AEA68169.1 | AEA71780.1 | PSEBR_a1946 | PSEBR_a5284 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.998 |
AEA68169.1 | ahcY | PSEBR_a1946 | PSEBR_a5283 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.960 |
AEA68169.1 | guaA | PSEBR_a1946 | PSEBR_a950 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative Transcription factor, ExsB family; Catalyzes the synthesis of GMP from XMP. | 0.661 |
AEA68169.1 | metE | PSEBR_a1946 | PSEBR_a4505 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.985 |
AEA68169.1 | metK | PSEBR_a1946 | PSEBR_a5272 | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.958 |
AEA70268.1 | AEA67839.1 | PSEBR_a3878 | PSEBR_a1635 | Aspartate transaminase (Aspartate aminotransferase). | Conserved hypothetical protein, GAF domain-containing protein. | 0.908 |
AEA70268.1 | AEA68169.1 | PSEBR_a3878 | PSEBR_a1946 | Aspartate transaminase (Aspartate aminotransferase). | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.922 |
AEA70268.1 | metE | PSEBR_a3878 | PSEBR_a4505 | Aspartate transaminase (Aspartate aminotransferase). | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.908 |
AEA70268.1 | metK | PSEBR_a3878 | PSEBR_a5272 | Aspartate transaminase (Aspartate aminotransferase). | Putative S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.908 |
AEA70268.1 | tpiA | PSEBR_a3878 | PSEBR_a776 | Aspartate transaminase (Aspartate aminotransferase). | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.464 |
AEA71767.1 | AEA68169.1 | PSEBR_a5271 | PSEBR_a1946 | Putative Transcription factor, ArsR family. | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.522 |
AEA71767.1 | metK | PSEBR_a5271 | PSEBR_a5272 | Putative Transcription factor, ArsR family. | Putative S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.834 |
AEA71780.1 | AEA68169.1 | PSEBR_a5284 | PSEBR_a1946 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.998 |