STRINGSTRING
ubiD ubiD ubiX ubiX ubiA ubiA AEA68755.1 AEA68755.1 AEA71942.1 AEA71942.1 AEA71959.1 AEA71959.1 AEA71961.1 AEA71961.1 AEA71958.1 AEA71958.1 AEA71957.1 AEA71957.1 rho rho ubiE ubiE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ubiD3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. (498 aa)    
Predicted Functional Partners:
ubiX
Putative decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
 
 0.994
ubiA
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
  
 0.960
AEA68755.1
Conserved hypothetical protein, membrane protein.
    
 0.931
AEA71942.1
Putative 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
 
  
 0.928
AEA71959.1
Putative iron-sulfur binding oxidoreductase.
  
    0.878
AEA71961.1
Putative acyltransferase, putative membrane protein.
       0.681
AEA71958.1
Hypothetical protein.
       0.675
AEA71957.1
Putative cation transport-related protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
       0.668
rho
Putative Rho transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
    0.503
ubiE
Putative ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
 
  
 0.497
Your Current Organism:
Pseudomonas brassicacearum
NCBI taxonomy Id: 994484
Other names: P. brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum CFBP 11874, Pseudomonas brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum str. NFM421, Pseudomonas brassicacearum subsp. brassicacearum strain NFM421
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