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pyrE pyrE pyrF pyrF pyrD pyrD carB carB pyrB pyrB carA carA AEA69690.1 AEA69690.1 AEA69688.1 AEA69688.1 AEA71818.1 AEA71818.1 AEA69357.1 AEA69357.1 prs prs
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (214 aa)    
Predicted Functional Partners:
pyrF
Orotidine-5-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.991
pyrD
Dihydroorotate oxidase (dihydroorotate dehydrogenase); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.989
carB
Carbamoyl-phosphate synthase (ammonia), large chain; Belongs to the CarB family.
  
 
 0.923
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.914
carA
Carbamoyl-phosphate synthase (glutamine-hydrolyzing), small chain; Belongs to the CarA family.
  
  
 0.910
AEA69690.1
Putative dihydropyrimidine dehydrogenase.
  
 
 0.885
AEA69688.1
Dihydropyrimidinase.
  
  
 0.868
AEA71818.1
Putative dihydroorotase.
  
  
 0.868
AEA69357.1
Putative Ribose-phosphate diphosphokinase.
  
 
 0.857
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.857
Your Current Organism:
Pseudomonas brassicacearum
NCBI taxonomy Id: 994484
Other names: P. brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum CFBP 11874, Pseudomonas brassicacearum subsp. brassicacearum NFM421, Pseudomonas brassicacearum subsp. brassicacearum str. NFM421, Pseudomonas brassicacearum subsp. brassicacearum strain NFM421
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