node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0410 | pntAA | PSEEN0410 | PSEEN0116 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Proton-translocating NAD(P) transhydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.613 |
PSEEN0410 | pntB | PSEEN0410 | PSEEN0114 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.614 |
PSEEN1365 | cobB-2 | PSEEN1365 | PSEEN2337 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | 0.901 |
PSEEN1365 | nadD | PSEEN1365 | PSEEN4829 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.907 |
PSEEN1365 | nadE | PSEEN1365 | PSEEN4920 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | NAD synthetase, prefers NH3 over glutamine; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.900 |
PSEEN1365 | nadK | PSEEN1365 | PSEEN1708 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative inorganic polyphosphate/ATP-NAD kinase NadK; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.905 |
PSEEN1365 | nudC | PSEEN1365 | PSEEN2184 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative NTP pyrophosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.915 |
PSEEN1365 | pntAA | PSEEN1365 | PSEEN0116 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Proton-translocating NAD(P) transhydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
PSEEN1365 | pntAB | PSEEN1365 | PSEEN0115 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyridine proton-translocating NAD(P) transhydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.900 |
PSEEN1365 | pntB | PSEEN1365 | PSEEN0114 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.903 |
PSEEN1365 | sthA | PSEEN1365 | PSEEN3711 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Soluble pyridine nucleotide transhydrogenase (NAD(P)(+) transhydrogenase [B-specific]); Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.907 |
cobB-2 | PSEEN1365 | PSEEN2337 | PSEEN1365 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.901 |
cobB-2 | nadD | PSEEN2337 | PSEEN4829 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.939 |
cobB-2 | nadE | PSEEN2337 | PSEEN4920 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | NAD synthetase, prefers NH3 over glutamine; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.932 |
cobB-2 | nadK | PSEEN2337 | PSEEN1708 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | Putative inorganic polyphosphate/ATP-NAD kinase NadK; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.928 |
cobB-2 | nudC | PSEEN2337 | PSEEN2184 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | Putative NTP pyrophosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.908 |
cobB-2 | pntAA | PSEEN2337 | PSEEN0116 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | Proton-translocating NAD(P) transhydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.911 |
cobB-2 | pntAB | PSEEN2337 | PSEEN0115 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | Pyridine proton-translocating NAD(P) transhydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.908 |
cobB-2 | pntB | PSEEN2337 | PSEEN0114 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.901 |
cobB-2 | sthA | PSEEN2337 | PSEEN3711 | Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the sirtuin family. Class III subfamily. | Soluble pyridine nucleotide transhydrogenase (NAD(P)(+) transhydrogenase [B-specific]); Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.915 |